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Unstable Personality Disorder | BudsByMail Canada
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Emotionally Unstable Personality Disorder (EUPD), also referred to as Borderline Personality Disorder (BPD), impacts social interactions, emotional stability, and may lead to impulsive or self-harming actions. Treatment can be expensive, with success rates between 35% to 50%. Researchers are investigating alternative therapies to supplement traditional treatments.

A promising addition to EUPD management is the incorporation of cannabis, commonly known as weed. It’s affordable, and its components may provide benefits for individuals with EUPD. Patients who struggle to afford multiple treatments might consider BudsByMail Canada for cost-effective cannabis options.

Key Takeaways:

  • Individuals with EUPD using THC or high CBD report positive outcomes in symptom management.
  • High doses of CBD (800 mg/day) and THC flower treatment can elevate circulating anandamide levels.
  • Dysfunction in the endocannabinoid system, which governs emotions and stress, plays a role in Emotionally Unstable Personality Disorder.

Emotionally Unstable Personality Disorder or Borderline Personality Disorder

EUPD is a mental health disorder that affects self-perception and interpersonal relationships, leading to challenges in everyday life. It features intense, unstable relationships, impulsivity, and a skewed self-image.

While the exact origins are not fully understood, factors like genetics, trauma, and neurotransmitter imbalances may contribute. Dysfunction in the endocannabinoid system, which manages emotional and stress responses, may exacerbate EUPD symptoms.

EUPD Treatment

Although guidelines indicate no medications are specifically effective for EUPD, clinicians often prescribe drugs such as antipsychotics and antidepressants.

Antipsychotic and sedative medications can sometimes assist with short-term crisis management or treat coexisting conditions. A notable percentage of patients with EUPD—up to 90% in certain studies—are on at least one psychotropic medication, including antipsychotics, antidepressants, mood stabilizers, and sedatives.

Polypharmacy is prevalent among these patients. Many of these medications come with side effects and are often used off-label for EUPD. While some medications may alleviate particular symptoms, they do not alter the overall prognosis of the disorder.

Cannabis-Based Medicine for EUPD (CBM)

Cannabis-based medicines are derived from the cannabis plant, containing cannabinoids, the active compounds such as tetrahydrocannabinol (THC) and cannabidiol (CBD). These products are used to treat various medical issues, including pain, inflammation, anxiety, and seizures.

Numerous studies are currently examining the effects on mental health. Research published in Frontiers in Psychiatry suggests that marijuana can alleviate depression and improve sleep quality and overall life satisfaction. These findings, among others, strongly advocate for further exploration into marijuana’s impact on various mental illnesses.

CBM for Unstable Personality Disorder

A narrative review and case series study in 2022 showcased the use of cannabinoids in managing EUPD symptoms for seven patients. Researchers explored the cellular and molecular mechanisms and reviewed current evidence for cannabis-based medicinal products (CBMP) as a potential treatment for EUPD.

Materials and Methods

ParticipantsDiagnosed with EUPD who had attempted at least one medication and one psychotherapy methodAt least one follow-up at a BudsByMail Canada clinic, with patient-reported outcome measures (PROMS) records.
CBM UsedDried Flower for inhalation (20-60g per month) Orally administered extracts with THC (9-10mg/day) and CBD (40mg/day).Formulation: Chemotype 1: High THC, low CBD. Chemotype 2: Balanced THC and CBD. Chemotype 3: High CBD, low THC.
MeasurementClinical Global Impression Improvement (CGI-I) Scale: A 1-7 scale where 1 indicates “very much improved” and 7 indicates “very much worse.”Patient’s Global Impression of Change (PGIC) Scale: A 1-7 scale where 1 signifies “no change or worse” and 7 indicates “a great deal better and considerable improvement.”

Researchers tailored dosing through gradual titration and provided guidelines for increasing the dose until satisfactory symptom control was achieved or side effects were noted.

Results

At a one-month follow-up, six participants reported improvements, with five rating their change as a six on the PGIC scale. Only one patient, who received a chemotype 2 oral extract, reported no benefit, suggesting that inhaled THC or higher oral CBD doses may prove more effective.

All participants tolerated the treatment well, with no side effects reported, which is crucial for adherence. Younger patients may feel more at ease with BudsByMail Canada despite societal stigma surrounding medical cannabis.

Hypothesis

Researchers propose that exogenous cannabinoids might aid in restoring the tonic activation of the endocannabinoid system (ECS) in the central nervous system (CNS). THC directly activates presynaptic CB1 receptors, and both cannabinoids bind to fatty-acid binding proteins (FABPs), which may slow the deactivation of anandamide.

High doses of oral CBD (800 mg/day) and patients treated with chemotype 1 flower show increased levels of anandamide in circulation. It remains unclear whether this results from CBD’s effect on anandamide transport or degradation or if it interacts with other molecular targets. Conversely, psychiatric medications generally take 2-3 weeks to show initial effects, with longer durations needed for patients to attain remission.

The rapid symptom relief can be vital during an “EUPD crisis,” when distressed individuals may resort to benzodiazepines and other anxiety medications. However, these drugs can lead to quick tolerance and dependence.

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Manage Changes in Behaviour with Bulk cannabis Via Mail-Order Marijuana Service

Cannabinoids effectively manage unstable personality disorders by targeting the ECS to maintain balance in anandamide breakdown. Patients with EUPD can gain advantages from purchasing cannabis online or affordable cannabis to help regulate their symptoms.

BudsByMail Canada with same-day delivery or mail-order options offers a blend of quality and affordability. Enjoy outstanding customer service from a supportive team and explore an extensive range of bulk cannabis strains, edibles, concentrates, and oils to enhance your experience. Buy cannabis online at BudsByMail Canada.

Frequently Asked Questions

Does cheap marijuana have poor quality?

No, price is not the only factor indicating product quality. You can evaluate quality by examining the product’s physical traits and trying it yourself. Some dispensaries offer lower prices through monthly or clearance sales. If a dispensary’s prices fall below the cannabis industry standard, it may raise quality concerns.

Does marijuana cause any adverse effects when managing BPD?

Marijuana has shown no adverse side effects reported by participants in the study. This is crucial for medication adherence, as a review of 36 studies indicated that side effects accounted for 28% of patients’ non-adherence to antipsychotics. A negative perception of antipsychotic medication was the second most common reason for intentional non-adherence, at 30.5%.

What is the quickest way to experience the effects of cannabinoids for an EUPD problem?

Smoking, vaping, and dabbing are the quickest methods to feel the effects of cannabinoids. In the study, participants utilized vaping to consume dried flower. While smoking and vaping produce similar effects, the distinction lies in inhaling smoke (from smoking) versus vapor (from vaping). Dabbing, which involves consuming concentrates, also leads to a rapid onset of effects.

How many times can I smoke or vape to manage my symptoms?

The effectiveness of cannabis strains and products varies based on individual responses. In the study, researchers permitted patients to adjust their daily dosage (between 0.5 and 2 grams per day) as long as they did not exceed the monthly limit. For extracts, patients recorded their daily intake.

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